Sen. Assist. Prof. Alexander Dimitrov, PhD | CV

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Education

  • 1997: MSc in Nuclear and Particle Physics, Faculty of Physics, Sofia University, Sofia, Bulgaria
  • 2010: PhD in Biophysics

Academic experience

  • 1997-2010: Assistant Professor in the Department of Analysis and Modelling of Excitability of Biological Structures, under Professor GV Dimitrov, Centre for Biomedical Engineering, Bulgarian Academy of Sciences
    3rd degree-1998
    2nd degree-2001
    1st degree-2009
  • 2010-2011: Assistant Professor in the Department of Biomechanics and Control of Movements, under Professor R Raikova, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences
  • 2011-2014: Senior Assistant Professor in the Department of Biomechanics and Control of Movements, under Professor R Raikova, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences
  • 2014-2021: Associate Professor in the Department of Motor Control (until 2018 – Department of Biomechanics and Control of Movements), under Professor R Raikova, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences
  • 2021-present: Senior Assistant Professor in the Department of Motor Control, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences

Languages

  • Bulgarian, Russian – mother tongues
  • English – fluent

Software development

  • Development of original numerical method for reducing the matrix of general type into three diagonal matrix. It provides solution of partial differential equations describing processes of excitability in myelinated axon on much larger scale.
  • An advanced model of myelinated axon was formulated.
  • Original software for model calculations was written in MATLAB.

Presentations at national or international conferences

  • 2000: Poster, “The effect of a near-membrane volume on generation of action potentials in myelinated nerve fibers” Workshop “Membranes and signalling”, Kiev, Ukraine, September 4-8, 2000
  • 2000: Poster “Changes in potassium concentration in myelinated nerve fibres”, 9th international symposium on Motor control, Varna, Bulgaria, October 8 –12, 2000
  • 2002: Oral presentation “A method for computation of processes in multicable structures” Scientific seminar “25 years biomathematics research group in BAS” December 17, 2002 IMI-BAS, Sofia
  • 2006: Poster “Not the membrane hyperexcitability but a prolonged depolarization of internodal membrane can induce spontaneous firing of peripheral axon under loss of potassium channels”, 5th FENS Forum of European Neuroscience, Vienna, July 8-12 2006
  • 2006: Poster “Mechanism of spontaneous repetitive firing of a myelinated axon induced by lack of potassium channels in a single internode”, XXVIII International Congress of Clinical Neurophysiology, Edinburgh, September 10-14, 2006
  • 2007: Oral presentation “Mechanism of spontaneous repetitive activation of a myelinated axon”, IX National Congress of the Bulgarian Society of Physiological Sciences, Blagoevgrad, Bulgaria, November 09 – 11, 2007
  • 2008: Oral presentation “A mechanism of axonal hyperexcitability”, European Pain School, Siena, Italy, June 15-22, 2008
  • 2008: Poster “Possible nature of nodal leakage current in mammalian myelinated axon”, 6th FENS Forum of European Neuroscience, Geneva, July 12-16 2008
  • 2008: Poster “Axonal hyperexcitability: an internodal mechanism predicted by computer simulation”, Current Trends in Biomedicine Workshop: “Understanding Pain: From Transduction to Sensation”, Baeza, Spain, October 6-8 2008
  • 2008: Oral presentation “Internodal mechanisms could explain axonal hyperexcitability in cases like neuromyotonia and allodynia, X Conf. Biomed. Phys. Eng. (with international participation), Sofia 16-18 October 2008
  • 2009: Poster “A model of sodium-potassium pump”, First National Conference on Biomedical and Bioprocess Engineering BM&BPE (with international participation) Sofia December 3-4, 2009
  • 2015: Poster “Hyperactivity of myelinated axons under changes in axo-glial interactions affecting periaxonal space width” XI National Congress of the Bulgarian Society of Physiological Sciences, Plovdiv, Bulgaria, October 09 – 11, 2015

Professional memberships

  • Bulgarian Society of Physiological Sciences
  • Union of Scientists in Bulgaria

Main research interests

  • Myelinated axon, Internodal processes, Problems of excitability, Pain, Bioelectrical phenomena, Fatigue, Extracellular potentials
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