Biomacromolecules and Biomolecular Interactions | Main research topics

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Microcalorimetric screening of serum/plasma proteome and erythrocytes in various pathologies. Application in biomedicine

Publications
Selected publications for the last 5 years:

  • Danailova A., Todinova S., Gartcheva L., Bogdanova D., Zlatareva E., Kalaydzhiev N., Milanov I., Krumova S., Taneva S.G.. Thermodynamic Signatures of Blood Plasma Proteome in Neurodegenerative Pathologies. Int. J. Mol. Sci., 24, 2023, SJR (Scopus):1.18, JCR-IF (Web of Science):6.208
  • Komsa-Penkova R., Krumova S., Langari A., Giosheva I., Gartcheva L., Danailova A., Topalova L., Stoyanova T., Strijkova V., Savov A., Todinova S.. Blood Plasma Calorimetric Profiles of Women withPreeclampsia: Effect of Oxidative Stress. Antioxidants, 12, 5, MDPI, 2023, DOI:https://doi.org/10.3390/antiox12051032, SJR (Scopus):1.084, JCR-IF (Web of Science):7.675
  • Krumova S., Todinova S., Taneva S. G.. Calorimetric Markers for Detection and Monitoring of Multiple Myeloma. Cancers (Basel) ., 14, 16, MDPI, 2022, DOI:https://doi.org/10.3390/cancers14163884, 3884. SJR (Scopus):1.349, JCR-IF (Web of Science):6.575
  • Todinova S., Nikolova B., Iliev I., Semkova S., Krumova S., Taneva S.G.. Thermodynamic behavior of breast cancer cell lines after miltefosine and cisplatin treatment. J. Therm. Anal. Calorim., 147, 14, Springer, 2022, ISSN:1388-6150, DOI:https://doi.org/10.1007/s10973-021-11094-6, 7819-7828. SJR (Scopus):0.639, JCR-IF (Web of Science):4.755
  • Komsa-Penkova R., Danailova A., Krumova S., Georgieva G., Giosheva I., Gartcheva L., Iliev I., Gartchev E., Kercheva K., Savov A., Todinova S.. Altered Thermal Behavior of Blood Plasma Proteome Related to Inflammatory Cytokines in Early Pregnancy Loss. Int J Mol Sci ., 23, 15, MDPI, 2022, DOI:doi: 10.3390/ijms23158764., SJR (Scopus):1.18, JCR-IF (Web of Science):6.208
  • Todinova S., Krumova S., Bogdanova D., Danailova A., Zlatareva E., Kalaydzhiev N., Langari A., Milanov I., Taneva S. G.. Red Blood Cells’ Thermodynamic Behavior in Neurodegenerative Pathologies and Aging. Biomolecules, 11, MDPI, 2021, DOI:https://doi.org/10.3390/biom11101500, JCR-IF (Web of Science):4.879
  • Krumova, S., Balansky, R., Danailova, A., Ganchev, G., Djongov, L., Gartcheva, L., Taneva, S.G., Todinova, S.. Calorimetric assay to follow colorectal cancer development in experimental rat models. Thermochimica Acta, 691, 2020, 178723. SJR (Scopus):0.558, JCR-IF (Web of Science):4.626
  • Langari A., Danailova A., Krumova S., Komsa-Penkova R., Golemanov G., Giosheva I., Gartchev E., Taneva S. G., Todinova S.. Aging-related changes in the calorimetric profile of red blood cells from women with miscarriages. Journal of Thermal Analysis and Calorimetry volume, 142, 2020, 1919-1926. SJR (Scopus):0.415, JCR-IF (Web of Science):4.626
Collaborators
  • National Specialized Hospital for Acive Treatment of Hematological Diseases, Sofia, Bulgaria
  • Multiprofile hospital for active treatment in neurology and psychiatry “St. Nahum”, Sofia, Bulgaria
  • Medical Unversity, Pleven, Bulgaria
  • University Obstetrics and Gynecology Hospital “Mother’s Home”, Sofia, Bulgaria
  • University Specialized Hospital for Active Treatment in Oncology, Sofia, Bulgaria

Nanomechanical, morphological and rheological properties of blood cells as biophysical markers for pathologies

Publications
Selected publications for the last 5 years:

  • Anika Alexandrova-Watanabe, Emilia Abadjieva, Ina Giosheva, Ariana Langari, Tihomir Tiankov, Emil Gartchev, Regina Komsa-Penkova, Svetla Todinova. Assessment of Red Blood Cell Aggregation in Preeclampsia by Microfluidic Image Flow Analysis—Impact of Oxidative Stress on Disease Severity. Int J Mol Sci ., 25, MDPI, 2024, DOI:10.3390/ijms25073732, JCR-IF (Web of Science):5.6
  • Giosheva I, Strijkova V, Komsa-Penkova R, Krumova S, Langari A, Danailova A, Taneva SG, Stoyanova T, Topalova L, Gartchev E, Georgieva G, Todinova S. Membrane Lesions and Reduced Life Span of Red Blood Cells in Preeclampsia as Evidenced by Atomic Force Microscopy. Int J Mol Sci ., 24, 8, MDPI, 2023, DOI:https://doi.org/10.3390/ijms24087100, SJR (Scopus):1.154, JCR-IF (Web of Science):6.208
  • Taneva Stefka G., Todinova Svetla, Andreeva Tonya. Morphometric and Nanomechanical Screening of Peripheral Blood Cells with Atomic Force Microscopy for Label-Free Assessment of Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis. Int. J. Mol. Sci., 24, Elsevier, 2023, DOI:https:// doi.org/10.3390/ijms241814296, 14296. JCR-IF (Web of Science):6.208
  • Alexandrova A., Abadjieva E., Tiankov T., Piroeva I., Atanasova-Vladimirova S., Langari A., Todinova S.. Modeling and Analysis of Image Data of Blood Clots Formed at Different Fibrinogen Concentration in Patients with Type 2 Diabetes Mellitus.. International Scientific Journal “Mathematical Modeling”, `7, 2, Scientific Technical Union of Mechanical Engineering, 2023, ISSN:2535-0986, 65-68
  • Alexandrova A., Strijkova V., Abadjieva E., Todinova S., Giosheva I., Langari A., Tiankov T.. Evaluation of the erythrocyte aggregation index in women with preeclampsia by the usage of the microfluidic device and specially developed rheological software. International Scientific Journal Industry 4.0, 5, Scientific Technical Union of Mechanical Engineering, 2023, 159-163
  • Abadjieva E., Alexandrova A., Tiankov T., Giosheva I., Todinova S.. Development of Software Application in the Evaluation of Erythrocyte Aggregation Studied with Microfluidic Device. International Journal Scientific Journal Machines. Technologies., 17, 6, Scientific Technical Union of Mechanical Engineering, 2023, 228-231
  • Dinarelli S., Longo G., Taneva S.G., Todinova S., Krumova S., Girasole M.. Surprising Structural and Functional Properties of Favism Erythrocytes Are Linked to Special Metabolic Regulation: A Cell Aging Study. Int. J. Mol. Sci., 24, 2023, SJR (Scopus):1.18, JCR-IF (Web of Science):6.208
  • Langari, Ariana, Strijkova, Velichka, Komsa-Penkova, Regina, Danailova, Avgustina, Krumova, Sashka, Taneva, Stefka G., Giosheva, Ina, Gartchev, Emil, Kercheva, Kamelia, Savov, Alexey, Todinova, Svetla. Morphometric and Nanomechanical Features of Erythrocytes Characteristic of Early Pregnancy Loss. International Journal of Molecular Sciences, 23, 9, MDPI, 2022, ISSN:1661-6596, DOI:10.3390/ijms23094512, SJR (Scopus):1.176, JCR-IF (Web of Science):6.208
  • Strijkova V., Todinova S., Andreeva T., Langari A., Bogdanova D., Zlatareva E., Kalaydzhiev N., Milanov I., Taneva S.G.. Platelets’ Nanomechanics and Morphology in Neurodegenerative Pathologies. Biomedicines, 10(9):2239, 2022, DOI:doi: 10.3390/biomedicines10092239, SJR (Scopus):0.87, JCR-IF (Web of Science):4.757
  • Strijkova-Kenderova V., Todinova S., Andreeva T., Bogdanova D., Langari A., Danailova A., Krumova S., Zlatareva E., Kalaydziev N., Milanova I., Taneva S.G.. Morphometry and stiffness of red blood cells – signatures of neurodegenerative diseases and aging. Int. J. Biological Macromolecules, 23, 1, MDPI, 2022, DOI:10.3390/ijms23010227, 227. JCR-IF (Web of Science):6.208
  • Andreeva T., Komsa-Penkova R., Langari A., Krumova S., Golemanov G., Georgieva G.B., Taneva S.G., Giosheva I., Mihaylova N., Tchorbanov A., Todinova S.. Morphometric and Nanomechanical Features of Platelets from Women with Early Pregnancy Loss Provide New Evidence of the Impact of Inherited Thrombophilia. International Journal o f Molecular Sciences, 22, MDPI, 2021, DOI:https://doi.org/10.3390/ijms22157778, SJR (Scopus):1.46, JCR-IF (Web of Science):5.924
Collaborators
  • National Specialized Hospital for Acive Treatment of Hematological Diseases, Sofia, Bulgaria
  • Multiprofile hospital for active treatment in neurology and psychiatry “St. Nahum”, Sofia, Bulgaria
  • Medical Unversity, Pleven, Bulgaria
  • University Obstetrics and Gynecology Hospital “Mother’s Home”, Sofia, Bulgaria
  • Institute of Optical Materials and Technologies “Acad. Jordan Malinowski”, BAS, Sofia, Bulgaria
  • Institute for the structure of matter, CNR, Rome, Italy

Interaction of nanomaterials with biological molecules and membranes

Publications:
Selected publications for the last 5 years

  • Krumova S., Petrova A., Koleva D., Petrova S., Stoichev S., Petrova N., Tsonev T., Petrov P., Velikova V.. Priming of Pisum sativum seeds with stabilized Pluronic P85 nanomicelles: effects on seedling development and photosynthetic function. PHOTOSYNTHETICA, 61 (SI), 2023, DOI:10.32615/ps.2023.033, 28-36. SJR (Scopus):0.584, JCR-IF (Web of Science):2.7
  • Krumova, S., Petrova, A., Petrova, N., Stoichev, S., Ilkov, D., Tsonev, T., Petrov, P., Koleva, D., Velikova V.. Seed Priming with Single-Walled Carbon Nanotubes Grafted with Pluronic P85 Preserves the Functional and Structural Characteristics of Pea Plants. Nanomaterials, 13, MDPI, 2023, DOI:https://doi.org/10.3390/ nano13081332, 1332. JCR-IF (Web of Science):5.719
  • Petrova N., Todinova S., Petrov P., Velikova V., Krumova S.. Foliar application of Pluronic P85‑grafted single‑walled carbon nanotubes induces thylakoid membrane structural remodeling. Acta Physiologiae Plantarum, 45, 12, 2023, 133. SJR (Scopus):0.566, JCR-IF (Web of Science):2.6
  • Taneva, S.G., Krumova, S., Bogár, F., Kincses, A., Stoichev, S., Todinova, S. J., Danailova, A., Horvath, J., Násztor, Z., Kelemen, L., Dér, A.. Insights into graphene oxide interaction with human serum albumin in isolated state and in blood plasma. International Journal of Biological Macromolecules, 175, Elsevier, 2021, ISSN:01418130, DOI:10.1016/j.ijbiomac.2021.01.151, 19-29. SJR (Scopus):0.97, JCR-IF (Web of Science):5.953
  • Velikova V., Petrova N., Kovács L., Petrova A., Koleva D., Tsonev T., Taneva S., Petrov P., Krumova S.. Single-Walled Carbon Nanotubes Modify Leaf Micromorphology, Chloroplast Ultrastructure and Photosynthetic Activity of Pea Plants. Int. J. Mol. Sci., 22, 9, MDPI, Switzerland, 2021, DOI:doi: 10.3390/ijms22094878, 4878. JCR-IF (Web of Science):5.924
Collaborators
  • Institute of Plant Physiology and Genetics, BAS, Sofia, Bulgaria
  • Institute of Polymers, BAS, Sofia, Bulgaria
  • Sofia University “St. Kliment Ohridski”, Sofia, Bulgaria
  • Institute of Optical Materials and Technologies
    “Acad. Jordan Malinowski”, BAS, Sofia, Bulgaria
  • Institute of Biophysics, HUN-REN, Szeged, Hungary
  • Ege University, Izmir, Turkey

Biofunctionalization of hard surfaces and optimization of their biocompatibility for medical applications

Publications
Collaborators

 

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