Past projects

The presented information is updated as of June 2014.

DepartmentFunding scheme. Contract number. DeadlineProject title. Coordinator
LPIBMNational program for development of the scientific potential MES, 2007-2009.Characterization of the membrane organization and dynamics through model systems composed of synthetic lipids and natural membrane extracts
BBIBulgarian National Science Fund, Project module NT-01/03: „Modified liquid and solid surfaces with adjustable nanostructures and properties”, 2006-2010.Colloid aspects of nanoscience: nanostructures at interfaces in bulk and in three-phase contact zones
PhMBilateral cooperation - Spain. Bulgarian Academy of Sciences and CSIC, Spain. 2010 – 2011Composition and functions of carotenoids in light harvesting complex of photosystem I of higher plants. Coordinator from IBPhBME: Assoc. Prof. Maya Velitchkova
QSAR&ММBulgarian Science Fund, № ДО-02-52/10.12.2008Computer system for advanced studies in molecular design, new materials and nanotechnology. Coordinator from IBPhBME: Prof. Ilza Pajeva
ESContract 29/4/10 between IBPhBME and Medical University - Varna, 2010-2012Contract 29/4/10 between IBPhBME and Medical University - Varna, 2010-2012
BIMMBulgarian Science Fund, № 7903, 1990-1994.Control of biotechnological and ecological systems
ESBulgarian Science Fund, № 1407/2004, B-1505/05, 2005-2009.Corticospinal motor excitability changes preceding reaction time movement
APBSDBilateral cooperation - Finland. Joint project between Tampere International Center for Signal Processing, Academy of Finland and Bulgarian Academy of Sciences, 2003-2005.Denoising of surface electrocardiogram signals for micropotential recovery
APBSDBilateral cooperation - Italy. Joint project between Institute of Biomedical Engineering, Consiglio Nazionale delle Ricerche and Bulgarian Academy of Sciences, 2010-2012.Detection and analysis of microvolt QRS and T wave alternans in electrocardiographic signals
PhMIndo-Bulgarian intergovernmental programme of cooperation in science and technolgy, F.M. University, Dept. of Biosciences and Biotechnology, with Prof. A. Misra, Б/Ин01, 2007-2012Developing a biosensor using photoexcitable membranes. Coordinator from IBPhBME: Assoc. Prof. Emilia Apostolova
ESBulgarian Science Fund, № ДТК 02/35, Coordinator: Assoc. Prof. Kiril Kolikov, 2010-2012Developing a device and a method for investigation of osmotic processes under electromagnetic influence with application for the destruction of tumor cell lines
BIMMBudgetary subsidy. Deadline: 2013Developing models for evaluation of the psychological preparedness by reaction time analysis. Coordinator: Corr. Memb. Prof. Krassimir Atanassov
BIMMBulgarian Science Fund, № 1501, 2005 – 2008.Development and testing of models for analysis, assessment and prognosis of the river systems pollution. Application to the basin of River Struma
BIMMMEW, №5407, 2006-2007.Development of a conceptual model for integrated water quality management. Application to the basin of River Struma
APBSDCooperation agreement between BAS and Schiller AG, Switzerland. Deadline: 2013Development of an automated quality control system for diagnostically useful 12-channel ECG recordings. Coordinators: Assoc. Prof. Irena Jekova, Assoc. Prof. Vessela Krasteva
LPIBMBulgarian Science Fund, № ДРНФ-02/2, 2010-2011Development of interdisciplinary scientific center for investigation of probiotics and their functional potential on microorganisms related to human health
BIMMBulgarian Science Fund, №ТН-647, 1996-1999.Development of the theory and practical application of variable structure systems for management of fermentation processes
PhMBulgarian Science Fund, № Б-1512, 2005-2009Dynamics and stability of the photosynthetic apparatus Coordinator: Assoc. Prof. Emilia Apostolova
PhMBudgetary subsidy, 2010 – 2012Effect of brassinosteroids on the photosynthetic apparatus of higher plants and its resistance to high-light stress. Coordinator: Assoc. Prof. Anelia Dobrikova
EAPBulgarian Science Fund, № K-707, 1997-2002.Effect of electric field on macromolecules in biological and model membranes
EAPBulgarian Science Fund, № K-411, 1994-1997Effect of electrical pulses at the interaction and transfer of poly ions through biological membranes
APBSDBilateral cooperation - Finland. Joint project between Tampere International Center for Signal Processing, Academy of Finland and Bulgarian Academy of Sciences, 2005-2007.Electrocardiogram arrhythmia analyses by automated heart beat classification
ESBulgarian Science Fund, № К – 447/94, 1994-1997Electrogenesis of human myelinated and demyelinated nerve fibres: mathematical modeling
ESBulgarian Science Fund, № К – 806/98, 1998-2001Electrogenesis of human myelinated and demyelinated nerve fibres: mathematical modeling
EAPBilateral cooperation - France. BAS-CNRS, Toulouse, France. 2006-2007Electrotransfer of anti-tumour agents and DNA
EAPBulgarian Science Fund, № K-31, 1991-1994.Electrotransfer of macromolecules
EAPDAAD and Bulgarian Science Fund Joint Project № DAAD-15, 2007.Exploitation and characterization of nanostrctured biomimetic surfaces as substrates for cultivating of osteoblasts
EAPBulgarian Science Fund, № N 5011, 1998-1999.Family of apparatus for electrochemotherapy of malignant tumors: laboratory and clinical studies – prototypes and construction
PhMBudgetary subsidy, 2004–2005Functional activity and structural stability of pigment-protein complexes of photosynthetic organisms under biotic and abiotic stress. Role of active oxygen species in inactivation processes. Coordinator: Prof. Dr. M. Velitchkova
BIMMDFG № 113/135, 2003 - 2005.Functional state modelling of biotechnological processes and their high quality control in the class of variable structure systems
BIMMBulgarian Science Fund, № МИ-1505, 2005-2009.Functional state modelling of biotechnological processes and their high quality control in the class of variable structure systems
BIMMBudgetary subsidy, 2013Generalized net modelling of processes, related the scene analysis, machine learning, data-mining environments, genetic algorithms and neural networks. Coordinator: Corr. Member Krassimir Atanassov
BIMMRoyal Society International Joint Project, № JP100372, 2010–2012Generalized net models and intuitionistic fuzzy sets in intelligent systems. Coordinator: Prof. Krassimir Atanassov
ESBulgarian Science Fund, № 1407/2004, 2004-2009Ghrelin-dependent modulation of contraction and membrane ionic currents in resistant arteries. Coordinators: Prof. D. Duridanova, Prof. Andon Kossev
BIMMBulgarian Science Fund, № ДМУ 02/4, 2009–2013High quality control of biotechnological processes with application of modified conventional and metaheuristic methods. Coordinator: Assoc. Prof. Olympia Roeva
EAPOP 'Human Resources Development, Grant BG051PO001-3.3.04/42, 2010-2011Implementation and use of new methods and approaches in the training of young researchers in the field of biophysics in order to increase their competitiveness and skills in applied fields such as agriculture, ecology and medicine. Coordinator: Assoc. Prof. Rumiana Tzoneva, Prof. Iana Tsoneva
BIMMDFG, № 113/109, 2000 - 2001.Implementation of intelligent technologies for control of biotechnical processes based on flow injection measurements
BCMBulgarian Science Fund, № ММ-520/95, 2 yearsIndeterminate problems in biomechanics – dynamic planar model of the human upper limb
LPIBMOP 'Human Resources Development, MES "Science and business" Д02-1025Indexing of the Journal of Geometry, Integrability and Quantization. Coordinator: Assoc. Prof. Ivaylo Mladenov
BBINATO, № EAP.RIG.982718, 2007-2010.Initial studies towards development of clinical biosensor for Alzheimer’s disease
QSAR&ММFP7 of EC, Project N266835Integrated in silico models for the prediction of human repeated dose toxicity of cosmetics to optimise safety - COSMOS. Coordinator for IBPhBME: Assoc. Prof. Ivanka Tsakovska
BIMMResearch Area (WOOD-PRO), EU № QLK5-CT-2002-30360.Integration of the Latvian State Institute of Wood Chemistry in the European
PhMBudgetary subsidy, 2010 – 2013Interactions and role of chlorophyll a in cytochrome b6f complex. Coordinator: Dr, Radka Vladkova
BIMMBudgetary subsidy. Deadline: 2013Intuitionistic fuzzy sets and logics. Coordinator: Corr. Member Prof. Krassimir Atanassov
QSAR&ММBulgarian Science Fund, № Л-910/1999Investigation of compounds, modulating drug resistance: modeling and prediction of bioactivity. Coordinator: Assoc. Prof. Ivanka Tsakovska
BBIMedical University - Sofia. 2008-2010.Investigation of pathogenetic disturbances in lung carcinoma using proteomic analysis
QSAR&ММBulgarian Science Fund, № Л-1416/2004Investigation of structure-function relationships of the transport P-glycoprotein and its substrates and inhibitors with application in drug therapy. Coordinator: Prof. Ilza Pajeva
PhMBudgetary subsidy, 2011 – 2013Investigation of the effect of UV irradiation on the photosynthetic apparatus of different ecotypes Arabidopsis thaliana. Coordinator: Assoc. Prof. Antoaneta Popova
BBINational, 2005-2007Investigation of the interactions of some photosynthetic proteins with artificial lipid membranes
BIMMBulgarian Science Fund, № И-1303/2003, 2003-2007.Knowledge representation with intuitionistic fuzzy logic for the purpose of medical diagnosis
LPIBMMES, 2005-2007.Lateral organization and asymmetric distribution of lipid molecules in native and model membranes
BBIBilateral cooperation - Hungary. Academy Exchange Project, with Prof. P. Ormos, Institute of Biophysics, Hungarian Academy of Sciences, 2010-2012Light-energy conversion and molecular dynamics in retinal proteins. Bioelectronical application
PhMBulgarian-German project (BMBF -WTZ BGR 99 / 008), funded by the International Bureau of the Federal Ministry of Education and Research – Germany (BMBF), 2000-2002Lipid-chlorophyll interactions. Coordinator for IBPhBME: Dr. Radka Vladkova
BIMMOP 'Human Resources Development, MES "Science and business" Д02-515L-lysine Neuro-Dynamic Optimal Control. Coordinator: Assoc. Prof. Tatjana Ilkova
EAPDFG, 436-100, 1993-1998 (2 projects)Mechanism of electrical permeabilisation
EAPDFG 436/113, 1999-2001.Mechanism of electroporative DNA and oligo transport through cell membranes and lipid bilayers
LPIBMOP 'Human Resources Development, MES "Science and business" Д02-733Membrane Fusion Based on the Stalk Model. Coordinator: Mariana Hadjilazova
LPIBMNational program for development of the scientific potential, MES, 2005-2006.Membrane microdomains. Role of ceramides in maintenance of their structure and functions. Model membranes – a necessary approach in investigation of the lipid organization in cells
APBSDJoint project with Schiller AG, Switzerland, 2006Methods and algorithms for registration, processing, analysis and classification of biomedical data, signals and patterns, and their implementation in e-clinical and life-saving equipment
BCMBulgarian Science Fund, № ДМУ02/5, 2009–2013Model of a muscle comprising of motor units, and software for simulating their control by a hierarchical genetic algorithm. Coordinator: Assoc. Prof. Hristo Aladjov
BIMMMEST, №5049, 5th FP of EC “Environment and Sustainable Development” Programme, 1998-2000.Model of integrated management for water quality and preservation of ecosystems
BIMMBulgarian Science Fund, № СС-71, 1997-2000.Modelling and establishment of a management system for a new kind of poultry farm
BIMMBulgarian Science Fund, № СС-338, 1993-1996.Modelling and optimization of biotechnological enterprise in the food industry
BIMMBulgarian Science Fund, № TS-1314, 2003-2007.Modelling and Optimization of Stirred Tank Bioreactors
BIMMThracian University – Stara Zagora, №03-1046/2003, 2003Modelling and variable-structured management of a fermentation process
BIMM, BCMBulgarian Science Fund, № ДИД-02-29, 2009–2013Modelling of processes with fixed development rules. Coordinator: Prof. Krassimir Atanassov
BIMMMarie Curie International Research Staff Exchange Scheme, № GA–2009–247541Models for ageing and technological solutions for improving and enhancing the quality of life. Coordinator for IBPhBME: Prof. Krassimir Atanassov
BBIBilateral cooperation - Hungary. Institute of Biophysics, Hungarian Academy of Sciences, Academy Exchange Project, with Prof. P.Ormos, 2003-2006, 2000-2003, 1996-2000.Molecular mechanisms of biological light energy transduction
ESBilateral cooperation - Germany. Institute partnership program of Alexander von Humboldt Foundation between the Institute of Biophysics of Bulgarian Academy of Sciences and the Neurology Clinic of Medical University of Hannover (MHH), 2003-2006.Motor cortex excitability in health and disease
BIMMOP 'Human Resources Development, MES "Science and business" Д02-792Multiple Objective Optimisation of Batch Cultivation of Saccharomyces cerevisiae. Coordinator: Assoc. Prof. Tatjana Ilkova
BCMBulgarian Science Fund, № В-1530/05.Non-invasive estimation of muscle fatigue
BIMMOP 'Human Resources Development, MES "Science and business" Д02-520Optimization of a Whey Bioprocess Using Neuro-dynamic Programming Strategy. Coordinator: Assoc. Prof. Tatjana Ilkova
BBIBudgetary subsidy, 2011-2012Optimized formation of monomolecular layers from the major light harvesting complex of photosystem II on the phase boundary buffer/air
LPIBMBulgarian Science Fund, № ДТК-212/08, 2008-2012Oxidative lipidomics: Influence of oxidative stress and antioxidant defense on the composition, structural organization and functional activity of membrane raft domains. Coordinator: Prof. Albena Momchilova
APBSDBilateral cooperation - Italy. Joint project between Institute of Biomedical Engineering, Consiglio Nazionale delle Ricerche and Bulgarian Academy of Sciences, 2004-2006.Pattern recognition in computerized electrocardiography and characterization of the repolarization phase
BBIJoint project of Sofia University and IBPhBME, BASPeptide nanostructures as effectors and regulators of the oxidations and reduction processes in plant cells
LPIBM, BBIBulgarian Science Fund, № ДТК-02/5, 2009-2013Phospholipase A2 and lipid peroxidation in neurodegenerative pathologies. How model membranes could contribute for elucidation of the mechanisms of lipid peroxidation on membrane organization? Coordinator: Assoc. Prof. Galya Staneva
PhMBulgarian Science Fund, № Б-1504, 2005-2009Photosynthetic apparatus under abiotic stress. Involvement of reactive oxygen species in inactivation processes. Coordinator: Assoc. Prof. Maya Velitchkova
BIMMOP 'Human Resources Development, MES "Science and business" Д02-522PID Controller Tuning based on Metaheuristic Algorithms for Bioprocess Control. Coordinator: Assoc. Prof. Olympia Roeva
LPIBMOP 'Human Resources Development, MES "Science and business" Д02-1021Proceedings of the International Conference Geometry, Integrability and Quantization. Coordinator: Assoc. Prof. Ivaylo Mladenov
BBIBilateral cooperation - Spain. Unidad de Biofisica (CSIC-UPV/EHU) y Departamento de Bioquímica, Universidad del País Vasco, Bilbao, Spain, with Prof. A. Muga, 2000-2002Protein folding/unfolding machinery
BBIBulgarian Science Fund, № ДМУ-02/7, 2009-2013Regulation of the functions and organization of the photosynthetic apparatus by brassinosteroids. Coordinator: Dr Sashka Krumova
APBSDBilateral cooperation - Italy. Joint project between Institute of Biomedical Engineering, Consiglio Nazionale delle Ricerche and Bulgarian Academy of Sciences, 2007-2009.Repolarisation phase in computerized electrocardiography: Analysis of T-wave morphology and QT dispersion
APBSDBulgarian Science Fund, 2009-2011.Research and development of high voltage generators for automated external defibrillators
BCMBulgarian Science Fund, № МУ-Л-1508/05.Research on the ability of the internodal structures to generate repetitive activation of myelinated axon
PhMBudgetary subsidy, 2011 – 2012Role of carotenoids for temperature stability of photosynthetic apparatus. Coordinator: Assoc. Prof. Emilia Apostolova
PhMBudgetary subsidy, 2004–2009Role of chlorophyll-lipid interactions for the assembly and functional stability of photosynthetic light-harvesting complexes. Coordinator: Dr. Radka Vladkova
APBSDMedical University - Sofia, Council of Medical Science, 2010-2011.Role of physical growth and pubertal maturation on the cardiovascular autonomic innervation in healthy children and young people
BBIBudgetary subsidy. Joint project of IBPhBME and IPBG, BAS, 2010-2012Role of supramolecular organization of PSII - LHCII complex in isoprene emitting plants and its relation to thermoprotection
BBIScience Fund of Sofia University. Joint project with Sofia University, Faculty of PhysicsSpectral and structural changes in photosystem II after heat and light stress
PhMBilateral cooperation - Spain. Joint project between BAS and CSIC-Spain, 2006-2007Spectral properties of the photosystem II reaction centre. Towards the assignment of pigment electronic absorbance bands. Coordinator for IBPhBME: Assoc. Prof. Maya Velitchkova
PhMNationalStability of pigment-protein complexes. Coordinator: Assoc. Prof. Anelia Dobrikova
PhMBilateral cooperation - Spain. Joint project between BAS and CSIC-Spain, 2004-2005Stability of the pigment-protein complex LHII from photosynthetic bacteria under extreme environmental conditions as probe by spectroscopic techniques. Coordinator for IBPhBME: Assoc. Prof. Dr. M. Velitchkova
APBSDBulgarian Institute of Metrology, Public commission, 2008-2009Standardised tester for examination of digital electrocardiographs
PhMBilateral cooperation - Hungary. Bulgarian Academy of Sciences and Hungarian Academy of Sciences (number 21), 2010-2012Structural and functional consequences of the modification of lipid, carotenoid and protein composition of photosynthetic membranes. Coordinator from IBPhBME: Assoc. Prof. Emilia Apostolova
PhMBilateral cooperation - Hungary. Joint project between Bulgarian Academy of Sciences and Hungarian Academy of Sciences (contract number 33), 2007-2009Structural consequences of the modification of lipid, carotenoid and protein composition of photosynthetic membranes. Coordinator for IBPhBME: Assoc. Prof. Emilia Apostolova
PhMBilateral cooperation - Hungary. Joint project between Bulgarian Academy of Sciences and Hungarian Academy of Sciences (contract number 29), 2004-2006Structural consequences of the modification of lipid, carotenoid and protein composition of photosynthetic membranes. Coordinator for IBPhBME: Assoc. Prof. Emilia Apostolova
QSAR&ММBulgarian Science Fund, № Л-518/1995Structure-activity relationships and molecular modeling of cationic drugs able to modulate multidrug resistance in tumors. Coordinator: Prof. Ilza Pajeva
EAPDAAD and Bulgarian Science Fund Joint Project № Д0 02/326Study of the influence of an applied electric field on the adsorption of adhesive proteins and endotelisation of nanostructure biomaterials for needs of tissue engineering and regenerative medicine. Coordinator: Assoc. Prof. Rumiana Tzoneva
EAPBulgarian Science Fund, № НТ-4, 2006-2008.Study of the interaction cell-nanostructured biomaterial (nanofiber nonwoven textile)
QSAR&ММBudgetary subsidy. Deadline: 2013Studying the interactions of human myosin using in silico methods. Coordinator: Prof. Ilza Pajeva
ESSwiss NSF Institutional Partnership Project № 7 IP 65642 (Program SCOPES): Establishing CSE in Bulgaria and Macedonia, 2002-2004.Swiss NSF Institutional Partnership Project № 7 IP 65642 (Program SCOPES): Establishing CSE in Bulgaria and Macedonia, 2002-2004.
APBSD, BIMMBulgarian Science Fund, 2010-2012.System for computer aid of the decisions for weaning critically ill ventilator dependent from mechanical ventilation
BIMMFP7, №203459, FP7 call: FP7-REGPOT-2007-1, 01.06.2008– 31.05.2011.The Implementation of Research Potential of the Latvian State Institute of Wood Chemistry in the European Research Area (WOOD-NET): TP 10: "Development of process control systems: functional state mathematical modeling, programming and optimization of bioreactor’s design both for solid state (including composting) and submerged fermentations"
ESInstitute of Neurology, London, grant G900630N from the MRC, 1989-1991.The molecular basis of nerve excitability in man: a patch clamp of ion channels and pumps in human myelinated axons
EAPBulgarian Science Fund, № K-1303, 2003-2006.Transmembrane transfer of drugs and DNA by electrical pulses
EAPBilateral cooperation - France. French-Bulgarian project, (CNRS-BAS), 2003-2005, Toulouse, France.Transmembrane transport of anticancer drugs and DNA by electrical pulses
EAPBulgarian Science Fund, № ДО 02/178Treatment of cancer cells and solid tumors by suitable choice of electrical pulses. Coordinator: Prof. Iana Tsoneva
EAPBilateral cooperation - FranceVesicles and Membranes. French-Bulgarian Laboratory, 1997-2002.

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